Migratol 24/7™ is a breakthrough nutraceutical product that nutritionally supports people with severe headaches.
No one really knows what the causes of agonizing and severe headaches are, but there are several theories and working concepts, (triggers or preconditions), and the effects. Sometimes, intense headaches may be accompanied by warning signs including nausea, vomiting, and sensitivity to light and sound.
There are some common threads, and variables among most of the theories. They include: a genetic or familial predisposition; being of the female gender; younger versus older, blood vessel anomalies (a rapid widening and narrowing of blood vessels in the brain and head); neurotransmitter imbalance; and potentially blood cell and blood component anomalies.
Some scientific researchers believe that migraines may be caused by some changes in the trigeminal nerve system. This is a nervous system major pain pathway. They further believe that imbalances in important neurotransmitters and brain chemicals, like serotonin, play a role. Serotonin has several functions and one of its most important functions is to regulate pain messages that travel through the trigeminal nerve system. Serotonin levels can drop during a headache. When this happens, it has been theorized that the trigeminal nerve releases substances known as neuropeptides which go to the outer covering of the brain. This set of actions causes some blood vessels to “open up” (dilate) and become inflamed. This is what can cause severe headache pain.
Magnesium is believed to play a major role. Magnesium is critical to nerve cell function. It has also been noted that magnesium levels drop preceding or during a intense headache episode. Decreased levels of magnesium may cause a misfiring of the nerve cells. All together, the drop in serotonin levels and magnesium levels play key roles in the development of a migraine condition or headache.
Migratol 24/7™ addresses the nutritional factors to support overall nerve health. Key ingredients for the nervous system include the essential element Magnesium, Feverfew, Butterbur Root, Grape seed Extract, and Vitamin B2. The special AM/PM formula provides nutritional support throughout the day.
The unique formula includes:
- Feverfew Select™: a very special, almost extinct variety of Feverfew.
- Butterbur Root: a plant that contains compounds that support blood vessel health.
- Magnesium Oxide: a terrific form of magnesium that helps to maintain water balance in the bloodstream and supplies elemental magnesium.
- Vitamin B2: an all-important essential B-vitamin for nervous system health.
- Vitamin B6: an essential vitamin that is involved in nervous system health, as well as the metabolism of serotonin.
- CoQ10: a naturally occurring antioxidant compound and is used for energy production within cells. CoQ10 is a fat-soluble nutrient that helps stabilize the cellular membrane.
- Grape Seed Extract: provides antioxidants that help promote a healthy vascular system.
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AM/PM Formula: the Right Way to take Supplements
Your body’s nutritional needs are different during the day and night. During the day your body needs nutrients that support a wide range of mental and physical endeavors. At night, your body and mind need to be able to relax, taking valuable time to rebalance the body during sleep. Restful sleep is one of nature’s greatest healing forces. Poor, restless sleep can result in all sorts of physical problems including; fatigue, poor healing, mental irritability, and inability to focus. We all know how great it is when we have a good night’s sleep. We feel refreshed and ready to engage the world with our best efforts.
The scientists at Bond Laboratories worked diligently to discover the ideal way to nutritionally support people who have Agonizing and Severe Headaches. They found that they needed to invent a formula that worked at supporting an active daytime lifestyle and promoted restful healing sleep.
AM Formula
The daytime formula contains significant amounts of Feverfew Select™, Magnesium Oxide, Butterbur Root, CoQ10, Grape Seed Extract, and Vitamin B2 (riboflavin), and Vitamin B6. This proprietary formula is superb at providing adequate Feverfew with supportive nutrients in a proprietary blend.
PM Formula
The night time formula is to be taken about one half hour before bedtime. It contains lower levels of Feverfew Select™ and Vitamin B6 to help promote sound relaxing sleep.
Feverfew…Back from the Brink of Extinction!
Feverfew Leaf is a proven botanical preventative treatment for agonizing and severe headaches. Only the very best Feverfew is used in Migratol 24/7™. We use a special variety of Feverfew, called Feverfew Select™ that has been thoroughly researched to provide the most promising benefits. This special variety is often cited in the best research literature where feverfew has been used to help people with intense headaches.
What does the research indicate?
Seventy percent of the patients in these studies report fewer attacks and less painful attacks. Researchers believe that certain varieties of Feverfew affect spasms of blood vessels in the head. Best results were obtained with continuous use.
How do I find Feverfew that is equal to that used in the clinical trials?
In January 2007, a 5-year National Institute of Health study was completed to help answer this question. The study compared the Feverfew materials used in the successful Hepinstall clinical trials in England in the 1980’s. The study was designed to develop a system for creating drug-like reproducibility in natural medicine without defined active ingredients.
The study was a success and as an added benefit the researchers were able to succinctly identify complex chemical differences using new, highly reproducible techniques as well as biological genetic markers, clearly identifying the material that was active in clinical trials versus the majority of feverfew on the market today… which was not active.
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Migratol 24/7™ has Feverfew Select ™
Feverfew Select™ is a unique variety of Feverfew that has the patented biochemical fingerprint of the research conducted through the National Institute of Health. Feverfew Select™ was created by reinvigorating the gene line in the successful Hepinstall clinical trials in England. Utilizing genetic technology, scientists working with Bond Laboratories are able to identify the chemical difference and genetic fingerprint of what made this specialized variety of Feverfew perform so well in prior clinical trials.
Migratol 24/7™ has exclusive rights to market the Feverfew Select™ material.
Superior Ingredients
In spite of the fact that Bond Laboratories purchased the entire Feverfew Select™ crop this last year, there was only a limited supply, resulting in a limited supply of Migratol 24/7™ for 2007. Hopefully, next year we will have a greater supply to help those in need of powerful nervous system nutritional support.
CoQ10
Coenzyme Q10 (CoQ10) is a fat-soluble nutrient that plays an important role in cellular energy production within the mitochondria. Coenzyme Q10 looks to be an excellent choice for providing nutritional support to those who have intense headaches. It can be given to almost any age group without fear of significant side-effects.
Butterbur Root
In a 2004 a study was published in Neurology that evaluated the effectiveness of Butterbur Root extract on migraine sufferers in a double-blind, placebo-controlled study involving 60 men and women who experienced at least three migraines per month. After 4 weeks without any conventional medications, participants were randomly assigned to take either 50 mg of butterbur extract or placebo twice daily for 3 months.
The results were positive: both the number of migraine attacks and the total number of days of migraine pain were significantly reduced in the treatment group as compared to the placebo group. Three out of four individuals taking Butterbur Root reported improvement, as compared to only one out of four in the placebo group. No significant side effects were noted.
Magnesium Oxide
Magnesium Oxide is one of the best kept secrets in magnesium nutrition. This unique ingredient supplies magnesium which has been show to be beneficial in nutritionally supporting nervous system and muscular health. While other nutraceutical companies use inexpensive forms of magnesium that may be poorly absorbed and transported in the blood, Bond Laboratories searched the world for pharmaceutical grade Magnesium Oxide. This special form of magnesium has been used in clinical studies.
Grape Seed Extract
Bond Laboratories uses a very high quality European Grape Seed Extract in Migratol 24/7™. Grape Seed Extract is renowned for its ability to promote healthy connective tissue by limiting the damage of free radicals. It also nourishes the cells of the blood vessels to enhance their elasticity. Blood vessels need to be able to withstand variations in pressure to properly carry blood to the cells. There are some researchers who believe that having blood vessels that can contract and expand in a healthy fashion is very important for a healthy vascular system. In fact, it may very well be that the inability for healthy blood vessels to respond normally to the stresses of life may exacerbate the tendency to have headaches and prolong their duration. Grape Seed Extract provides excellent nutritional support for the blood vessels and may help them expand and contract in a normal fashion.
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